The UK has an internationally recognized community of peptide scientists working on cutting-edge research that is relevant to human health and well-being. This special issue brings together four Reviews and seven research articles highlighting Emerging Peptide Science from laboratories across the country.
The first Review from the group of Professor Mark Bradley at the University of Wolverhampton investigates the emerging field of bioportides, a bi-functional sub-class of cell penetrating peptides that can also act as regulators of protein-protein interactions. The second Review from the group of Dr Craig Jamieson at Strathclyde University describes the development of novel synthetic peptide hormones that can induce therapeutically desirable physiological effects in humans.
It has become increasingly evident that food proteins and peptides can have beneficial physiological effects. The most common of these are the anti-hypertensive peptides, which act by inhibiting the activity of the enzyme ACE, thus reducing production of the potent vasoconstrictor angiotensin II. The results of a number of studies show that peptides can induce these effects in vitro and in vivo, with some even showing measurable clinical benefits in humans.
Although it is clear that the intestine is able to absorb di- and tripeptides there has been much less evidence examining the absorption of higher molecular weight bioactive peptides. However, the evidence available suggests that these are absorbed by paracellular diffusion.
Another interesting area of study involves the use of peptides as skin care products. These can be taken orally as dietary supplements, as nasal sprays, or as injections. They can be used to improve the appearance of the face, including wrinkles and dark circles around the eyes. Moreover, they can also be applied topically as creams or ointments. These skin care products should be left on the skin for a long time to ensure that they penetrate deeply into the tissues. This way, they can help reduce the appearance of fine lines and wrinkles, as well as brighten up the complexion. It is also recommended to pair them with a good moisturizer. This will allow the peptides to work effectively. It is also important to remember that the FDA does not regulate dietary supplements as they do medications, so people should be careful when purchasing them. In addition, they should talk to a doctor before using them. The doctor can recommend the right dosage for each individual. This will prevent them from overdoing it, which could cause an adverse reaction. uk peptides